Profile

The interest in bacterial biofilms has dramatically increased in recent years as we begin to recognise their importance for recurring, difficult to treat infections, as well as their contribution to the development of antibiotic resistance.

Historically antibiotics have only been tested in rather simple tests against non-sessile (planktonic) bacteria, thereby neglecting the fact that over 99.9% of the bacterial biomass exists as biofilms.

The Adelaide Biofilm Test Facility is South Australia’s first facility dedicated to test compounds, formulations, coatings, wound dressings and other materials for their efficacy to inhibit or remove bacterial biofilms.

Unique in Australia, our Facility combines the expertise of microbiologists, pharmaceutical scientists and clinicians for best end user outcomes.

 

Products and services

The PC2/OGTR certified Adelaide Biofilm Test Facility offers standardised and customised in vitro and in vivo biofilm tests for most common pathogens including clinical isolates such as methicillin resistant Staphylococcus aureus (MRSA).

Selecting an appropriate biofilm model that reflects their real environment as closely as possible we test compounds, pharmaceutical preparations and other materials and evaluate their antibacterial effects against biofilms.

We understand that customised solutions often better address the requirement for particular applications in industry, academia, for health care providers and other parties. Please contact us to discuss your requirements.

 

Type Manufacturer Model Technical Specifications
Automated liquid handling system Eppendorf EpMotion 5070  
Multimode reader Perkin Elmer EnSpire Absorbance, fluorescence and luminescence
Multimode plate reader and imaging system BioTek Cytation 5 CO2, temperature and shaking control
Fluorescent microscope Olympus    
Autoclaves, incubators     various temperatures
Separate microbial cells and tissue cultures infrastructure      

We offer a range of biofilm models with high, mid, or low throughput capabilities including but not limited to:

Name Description
96 well plate high throughput biofilm assays various quantification techniques available
Calgary/MBEC model  
Tube model  
Artificial dermis  
Semi-solid wound biofilm model  
Lubbock wound model  
Flow cell  
Whole animal toxicity and infection model in C. elegans  

 

Contact

Dr Nicky Thomas

Facility Manager
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Location

Basil Hetzel Building, Level 4
University of South Australia
City East Campus
Frome Rd
Adelaide SA 5000