Adelaide Spectroscopy provides a comprehensive service of nuclear magnetic resonance (NMR) spectroscopy for academic and industrial clients who require characterisation and analysis at the molecular level.

Based across three nodes at the University of Adelaide, Flinders University and the University of South Australia, Adelaide Spectroscopy can offer hands-on access to state-of-the-art spectroscopic facilities, or a full service run by experienced technicians.

The equipment is suitable for the analysis of a wide range of molecular structures, from small organic molecules to large biological structures such as peptides and proteins.


Products and services


A comprehensive range of solution NMR experiments including:

  • Rapid, routine 1-D and 2D 1H and 13C NMR spectra run on an open-access, fully-automated 500 MHz NMR spectrometer.
  • A full range of multinuclear (broadband) NMR experiments using the 500MHz Agilent “oneNMR” probe that can be tuned to different nuclei including 15N, 19F and 31P automatically.
  • State-of-the-art cryo-enhanced 600 MHz NMR experiments including a suite of protein backbone assignment and protein C13/N15 experiments with excellent water suppression for biological applications such as protein structure determination. Use of the cryo-enhanced service gives distinct improvements in sensitivity and peak resolution in 1-D and 2-D spectra, as well as allowing excellent 1-D NOE and 2-D COSY, HSQC, HMBC and NOESY spectra for the chemist.



  • Can perform a range of tasks related to diffusion NMR including diffusion ordered spectroscopy (DOSY), polymer molecular weight distribution determination, nanoparticle size distribution determination, etc.
  • Standard T1 and T2 relaxation experiments with addition of spoiler recovery, can be used for relaxation ordered spectroscopy (ROSY), characterising relaxivities of contrast agents, etc.
  • Magnetic Resonance Imaging of liquid or semi-solid samples which can fit inside of 5 or 10 mm NMR tubes. Small biological systems such as plant roots, are ideal for this system. Experiments can be used to validate MRI contrast agents. Rapid imaging capabilities can be used to characterise time-dependent processes. Ultra-short echo time sequences can be used to characterise materials, complementary to micro-CT.



A comprehensive range of solid state and solution NMR experiments including:

  • Fully-automated 600 MHz NMR spectrometer used to run routine solution spectra (1H, 13C, multinuclear) as well as advanced 1, 2 and 3D spectra.
  • Manually operated 400 MHz NMR spectrometer used to run routine solution spectra (1H, 13C, multinuclear) as well as advanced 1, 2 and 3D spectra.
  • The manually operated 400 MHz NMR spectrometer is also equipped with solid state capabilities using either 4mm or 7mm rotors for multinuclear experiments.


Type Manufacturer Model Technical Specifications
University of Adelaide
600 MHz NMR Spectrometer Agilent DD2 Console with Cryoprobe Cryo-probe for cryo-enhanced, high-resolution 1-D, 2D and 3-D NMR experiments suitable for biological samples.
500 MHz NMR Spectrometer Agilent DD2 console with a oneNMR probe Routine characterisation of small molecules using 1-D and 2D multinucelar NMR experiments suitable for small organic molecules. Fitted with an autosampler.
University of South Australia
600 MHz NMR Spectrometer Bruker AVANCE III HD 600 standard bore State-of-the-art 5 mm and 10 mm microimaging and diffusion probe equipped for a range of nuclei (1H, 19F, 13C etc).  The diff30 diffusion gradient set (11.7 T/m maximum Z-gradient) can measure spectrally resolved molecular self-diffusion coefficients as small as 10-13 m2/s.  The micro5 micro-imaging gradient set can perform a range of MRI experiments on 5 or 10 mm (diameter) samples including spin echo images, gradient echo images, rapid (RARE) single shot images, ultra-short echo time images (UTE), velocity/ flow images, diffusion images, etc.
300 MHz NMR Spectrometer     Bruker AVANCE II Capability to study both solution-state (by the majority of 1D and 2D experiments) and solid-state (cross polarisation/magic angle spinning) samples targeting nuclei such as 1H, 13C, 15N, 27Al, 29Si and 31P.  Can be used for quantitative measurements and is ideally suited for product quality control, structure elucidation, evaluation of compound purity and for monitoring changes in materials that may occur over time.
Flinders University
600 MHz NMR Spectrometer Bruker AVANCE III 600 Full range of 1 and 2D experiments including multinuclear and variable temperature capabilities. Autosampler. Probes available – 5mm inverse triple resonance (CHN), 5mm multinuclear inverse, 5mm multinuclear
400 MHz NMR Spectrometer Bruker AVANCE III 400 Full range of 1 and 2D experiments including multinuclear and variable temperature capabilities. Probes available – 5mm multinuclear inverse. Solids probes 4mm and 7mm rotors
Name Description
1-D 1H and 13C NMR Spectroscopy Basic characterisation of small organic molecules.
Cryo-enhanced 2-D COSY, HSQC, HMBC and NOESY NMR Spectroscopy High-resolution structure determination of complex biological macromolecules.
Multi-nuclear NMR Spectroscopy Detection of a range of nuclei such as 15N, 19F and 31P.
Solid-state NMR spectroscopy Multinuclear solids probes (4mm, spinning to 15kHz) and 7mm (spinning to 7kHz)
Multi-nuclear Diffusion experiments Diff30 probe (5 mm) dedicated for diffusion studies of molecular weight, size, shape, charge, binding events, chemical exchange etc of/in polymers, surfactants, particles etc and for liquid/solvent diffusion/flow in porous materials.
Multi-nuclear Micro-imaging experiments Micro 5 micro-imaging probe (5 mm) dedicated for high-resolution micro-imaging studies of structure and dynamics in micro- and macro-heterogeneous soft and hard materials.


Mr Philip Clements

Facility Manager


The University of Adelaide
North Terrace Campus
Badger building (ground floor)
Victoria Drive
Adelaide SA 5000