NIBEC offers researchers, industry and health professionals, unique non-invasive solutions to measure new and existing biomarkers of health and disease.
Using breath analysis techniques, biomarkers can be measured longitudinally without the need to stop experiments and harvest cells or tissue. Breath analysis is ideal for quantifying biomarker activity in difficult to access organs such as the small intestine and liver.
Using breath testing in an animal or clinical study? We can provide you with all the tools needed for sample collection. Samples are stable at room temperature, and can be delivered to us at your convenience.
NIBEC has state-of-the-art mass spectrometers that can be used to measure a range of compounds in gas samples. and utilizes isotope ratio mass spectrometry (IRMS) for 13CO2 /12CO2 measurements and a breath-tracker for hydrogen and methane analysis.
We house the only selected ion flow tube mass spectrometer (SIFT-MS) for real-time breath Volatile Organic Compound (VOC) measurement in South Australia.
Breath testing is a cutting edge research solution that will give you the competitive advantage in your research program.
At NIBEC, we offer non-invasive solutions at all stages of the research pipeline, from in vitro cell studies, to animal models and clinical research.
|Stable Isotope Biomarkers||
We have a battery of validated non-invasive breath tests available for analysis of gut health, liver function, detection of infection, inflammation, cell metabolism and fermentation patterns.
These include the clinically validated 13C-urea breath test for H.pylori infection, the 13C-Octanoate and 13C-acetate breath tests for measurement of gastric emptying.
We can also work with researchers to develop new, tailored breath tests for your novel, non-invasive biomarker candidates.
|Breath Tracking for H2/CH4||
The breath tracker is a clinically validated instrument that can be used to quantify sugar intolerances (eg. lactose or fructose intolerance), small bowel bacterial overgrowth and orocaecal transit time.
|Volatile Organic Compounds (VOCs)||
VOCs are produced and expired as bi-products of various cellular processes, and can be indicative of altered states of health and disease.
The technology to measure VOCs has advanced so that pre-extraction or derivatisation is no longer required.
Using Select Ion Flow Tube (SIFT) Mass Spectrometry we can provide instantaneous, real time analysis of VOCs in gas samples including mammalian breath, as well as headspace of plasma, urine or cell cultures.